Calbindin-D9k

Synonyms: CaBP-9k; CALB3; S100D

Description:  Vitamin D-dependent calcium-binding protein. Functions as a cytosolic buffer for Ca²⁺ ions in duodenal enterocytes and facilitates transepithelial active transport of Ca²⁺ ions. Also present in pig uterus and placenta. Binds two equivalents of Ca²⁺. 

Biological roles: fetal calcium uptake; uterine contractions; calcification of bone and teeth; calcium transport and uptake in mammalian intestine.

Species:        Porcine

Amino acid sequence:    *SAQKSPAELK SIFEKYAAKE GDPNQLSKEE LKQLIQAEFP SLLKGPRTLD DLFQELDKNG DGEVSFEEFQ VLVKKISQ

Modified amino acids:    *) N-terminally acetylated

Purity:    >98% by HPLC

Molecular mass:    8840.0

Form:    White lyophilized solid. 

Solubility:    Buffer

Storage:    Freezer (-20°C). Following reconstitution, aliquot and freeze (-20°C).

References:    [1] Schroder, B., et al. 1996. J. Physiol. 429, 715. [2] Hitchman, A.J.W., and Harrison, J.E. 1972. Can. J. Biochem. 50, 758.