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2002-2007

Sequence comparison of Diazepam Binding Inhibitor (DBI) from different species.

The comparisons indicate high conservation and high sequence similarities.

 

Residues 1-50

Pig    SQAEFEKAAE EVKNLKTKPA DDEMLFIYSH YKQATVGDIN TERPGILDLK

Human  SQAEFEKAAE EVRHLKTKPS DEEMLFIYGH YKQATVGDIN TERPGMLDFT

Rat    SQADFDKAAE EVKRLKTQPT DEEMLFIYSH FKQATVGDVN TDRPGLLDLK

 

 

Residues 51-86

Pig    GKAKWDAWNG LKGTSKEDAM KAYINKVEEL KKKYGI

Human  GKAKWDAWNE LKGTSKEDAM KAYINKVEEL KKKYGI

Rat    GKAKWDSWNK LKGTSKENAM KTYVEKVEEL KKKYGI

 

 

 

Superimposition of the bovine (cow, c.), yeast (y.) and Plasmodium falciparum (p.f.) apo-DBI structures. [Faergeman et al., Mol Cell Biochem. 2006 Sep 30.]

 

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