Zn₇-Metallothionein-1A

Synonyms:    Zn₇MT-1A; Zn-MT-I.  

Description:    Noncovalent complex with 7 zinc ions. All Cys-residues are in the form of  thiolates, which participate in the binding of seven Zn²⁺ ions.

Species:    Rabbit.

Amino acid sequence:    *MDPNCSCATG NSCTCASSCK CKECKCTSCK KSCCSCCPAG CTKCAQGCIC KGASDKCSCC A

Modified amino acids:    * The N-terminal methionine is acetylated. All Cys-residues are in the form of  thiolates, which participate in the binding of seven Zn²⁺ ions.

Molecular mass:   6583.07

Form:    Lyophilized. 

Purity: Contains 7 Zinc ions per molecule of metallothionein-1A.

Solubility:    Buffer at pH 7-8.

Storage:    Freezer (-20° C). Protect from moisture. In solution at neutral pH and in the presence of oxygen metallothionein is sensitive to oxidation and solutions should not be stored.

References:   Hunziker, P. E., Kaur, P., Wan, M. & Kanzig, A. (1995) Primary structures of 7 metallothioneins from rabbit tissue, Biochem. J. 306, 265-270.